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Martens and his team modeled that scenario in mice who'd been born free of microbes. They seeded the mice's guts with a human gut microbiomeand and
then fed them a high fiber diet: raw milled corn, whole wheat, whole soybeans and oats.
It's about as raw of a diet as you can get.The human equivalent: double our recommended daily intake of fiber. It's a lot of kale.
That extreme high-fiber diet helped keep the mucus barrier intact.But in mice that had zero fiber-or the kind of soluble fiber typically added to
processed foods-the fiber-eating members of the gut dwindled.Their absence opened up more real estate for mucus-munching bacteria,
which boomed in number, and tore through the protective mucus wall-leaving intestinal cells open for microbial attack.
The study is in the journal Cell. The results suggest that the recent history of your diet could predispose how you react to an enteric pathogen.